Hypervalent iodine mediated alkene difunctionalization of vinylphenols: diastereoselective synthesis of substituted indoles and indolizines.
نویسندگان
چکیده
A hypervalent iodine mediated alkene difunctionalization reaction of vinylphenols has been developed. The chemistry is applicable to a wide range of substitutions on both the alkene and nucleophile substrates, enabling the rapid synthesis of 3-substituted indoles and 2-substituted indolizines in good yields and high diastereoselectivities under metal-free conditions.
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 51 29 شماره
صفحات -
تاریخ انتشار 2015